Can i install all my VST's on a separate Drive ?

I have a Spare 160GB SSD and i want to install all my vst on this Drive so they will always be in one place and making updating hassle free. Reason for doing this is because i have everything going to my C drive in Cake folder and some in different folders on the drive. i want to put all meaning about 30 vst on the spare drive so i can update and call it the V drive and have every vst reside on this drive. REASON #2 MY MAIN REASON for doing this when i want to do a fresh install of the OS i don't have to spend the next 2 DAYS installing VST Software. I DO HAVE A CLONE of my drive but then when i update stuff i have the load the old Drive update do this do that too much hassle Thanks guys

FWIW, when you do a fresh/new OS install you "MAY" have to reauthorize those VSTs, even though they still are installed. Installing the corresponding libraries on another drive (if they are instrument VSTs, is a time saver, those wont have to be redone. As Progmatist said , some VST installers plant files all over the place, including registry entries, so with a fresh OS install,the VST may not work ,since its registry entry is not there... BUT YMMV...

+2 to Jims comments, although I am using a 1.5 Tb drive for my libraries now, at present, holds 980 Gig of samples , . I do , however, have a 256 gig SSD for my C: drive and was able to get rid of my redi-boost and bumped my WE HD score to 6.8

Just be aware that even though you may have a separate drive for your plug-ins that changing a system drive still may require you to reinstall or re-authorize.

 
That's another good point...

This time around I decided to keep them on the C drive in C:\program\VSTplugins and C:\program(x86)\VSTplugins. In the process I realized that I could dictate where all of the VSTs (32 & 64) went except for a couple of instances. I ended up with C:\program files (x86)\steinberg\VSTplugins (or similar) folder with something in WaveLab7 and there was one of the Komplete7 packages that made it's own VST folder and IIRC one of the T-Racks singles.

 
With a 64Bit OS, you really have to pay attention when installing VST Plugins.
There's absolutely no standard for the installers.
 
-Some will ping the registry to find the default VST Plugins folder.
-Some will put the dlls in a subfolder under the main install folder.
-Some will use C:\Program Files\Steinberg\VstPlugins (which is a throw back to many years ago)... even though you have no Steinberg software.
-Some will place both the 32Bit and 64Bit dlls in the same folder.
-Some will create a VST Plugins folder under C:\Program Files
-Etc...
 
If you just accept the default install locations, you can wind up with a mess.