Jeff's drawing may help if you have a problem ground loop between the interface and the amplifier.
Here's the thing - ground loops are not bad, and in fact they are virtually unavoidable. The problem really stems from some very poor design/manufacturing choices made by companies that haven't read the AES standards for interconnections yet... well, or ancient Bell and BBC documents (the ancients are stealing our ideas!)
Before you make up new cables may I suggest a simple test to find the problem?
Disconnect the amplifier inputs and crank the amplifier all the way up and listen - do you hear hum, or just white noise? If you hear hum then there is a problem between the interface and the amplifier, and Jeff's cable will probably solve it.
If not then the problem exists elsewhere, so you want to add gear back in, one link at a time. So now connect the interface to the amplifier, but leave the rest of the interface connections disconnected. Still no hum? Now add the rest of the interface connections, one at a time. If it turns out that you get hum after adding two more connections then disconnect the first one and see if the hum goes away.
I recently had a problem where I only had hum when I had both left and right line inputs connected to a Presonus Firebox. Following that test procedure I discovered a bad connection is one of my cables. A couple minutes with the soldering iron solved it.
One last thought (at the risk of repeating myself) DO NOT, UNDER ANY CIRCUMSTANCES, USE ANY TRICK THAT DEFEATS THE SAFETY GROUND!!!!!! Sorry, but this is an only wives tale that still floats around the internet from time to time.... so I figured I'd be proactive<G>!
Power line noise is annoying, but it is usually quite easy to resolve, once you find the source(s). Please let us know how it turns out.
And if you are looking for some additional reading, the top documents on this topic include (among others):
Dennis Bohn's
Rane Note #110 - a classic, well regarded paper that covers the topic well!
Bill Whitlock's
Troubleshooting Guide, and App Notes on
Interconnections and
Hum and Buzz (actually, everything on their web site!)
There are many others, but these will get you started<G>!