Coil Split EQ?

Not 100%, though there are one or two pedals about that claim to be able to make a humbucker sound like a single coil and eq can get you some way there. And Billy Gibbons is reputed to have used a bank of graphic equalisers to make whatever collection of oddball guitars he uses on stage sound pretty much like a Les Paul.

I suggest you take a look at Seymour Duncan's pickup comparison chart - http://www.seymourduncan....ickup-comparison-chart

It has a rough indication of comparative output levels, bass/mid/treble and resonant peak for lots of their pickups.

As a general rule though, single coils tend to have less mids, a bit less bass and more top, and the strongest frequencies/point of maximum Q tends to be both narrower and higher than humbuckers. Guitars put out very complex waveforms though, and getting something like convincing Strat "quack" and frequency cancellation when two pickups are on may be difficult. The easiest sort of eq fix might be to make a bridge 'bucker sounding more like a Tele bridge or a P90.