It's time to admit defeat. I've managed to use workarounds to force my old SPS-25 to work with Windows 10 but Microsoft's latest update seems finally to have administered the coup de grâce to my faithful old audio interface. So is there a newer like-for-like product I can replace it with? I don't need any more functionality than existed in the SPS-25.
 
Steve

http://forum.cakewalk.com/Cost-Effective-2x2-Audio-Interface-m3455099.aspx
 
 
Or, even better, browse through Sweetwater's catalog of USB interfaces:
 
http://www.sweetwater.com/c695--USB_Audio_Interfaces
 
Once you've got your list down to two or three candidates, come back here and share your specific needs/concerns and we'll try and help you narrow it down further.

You may not have to give up on your interface...
 
I have an Edirol UA-25EX that's working under Win10.  The secret is that you have to be connected to the net in order to update the driver.  There's no place to download the driver and install/update it manually.  The good news is that it then seems to just come up and work without having to do anything intentional.