Try doing a Save As and seeing if creating a new project file corrects it. If that fixes whatever was wrong with the original project - you can just do a rename of the original project file to something else and then rename the newly created one back to the name of the original.
So, if the Fred project may have some project file corruption, open Fred, Save As Fred_new, and if Fred_New behaves properly then close Fred_New, rename Fred as Fred_Old, and then rename Fred_New to its original name of Fred (so it again matches the Project Folder name of Fred.
Hope that wasn't too confusing - it's only 6:30 AM here and no coffee yet.
Bob Bone