So many good ideas - I am just a beginner when it comes to acoustic stuff, but I am in a country band that records acoustic guitar tracks, fiddle, mandolin, banjo and the like, so I have a good interest in the subject.
I would say 'NO' to plugins, 'it depends' to double micing and 'probably not' to pickups - depending upon the music genre and function of the track.
The two my input echo are jb101 and LJB - but maybe add a few different thoughts.
I like the idea to run scratch tracks first 'in easy mode' when I am writing. I use a PRS 24 trem which has a piezo. Not electric, but it helps me hear the notes in a relative context.
I like form function. I have a touch screen that keeps me away from keyboard and mouse, and a nice swivel chair. I position my mics so that I can turn around into them - about 110 degrees - however, I also adjust my screen so that see it, and my right hand can touch it really easy. I have a fixed point on the wall so as I turn, I lock into the same place, every time.
Mics - its easy once you have a few to think 'it can't be my mics', but from my experience, it is highly possible that what I was reaching for in a sound, required the same mic that I was listening to, used by the artist in a session I got the idea from. I use stereo pairs (of what I can afford) of large diagram condensers (C414s) or ribbons (R121's), for a fuller sound yet maintain a nice presence. That gives me width and fullness. When its solo or single channel, I tend to use one of each, and blend the two instead of using EQ if I can, and I usually can. To me, thats a goal - NO EQ. As of late, FET based mics have piqued my interest because they can have a really nice effect in the presence area. I am looking at a Mojave 301 FET today and will pick up a pair within the next few months. I know - pricey for some, but I can cover a house with chalk or paint. When rain scrutinizes the effort, paint wins.
It is also probable that micing technique can help improve the sound in good ways, in which you eluded to in the subject with pairs - but there is more out there you can explore. From the simplest 12th fret - single large diagram mic, to stereo pairs and all their positions and configurations like near coincidence and the like. Each mic also exhibits characteristics that enhance a certain range close in, and further away. Inches count. Good folks here on the forum have written a plethora of priceless info on this topic, far smarter than I could ever be on the subject and I use that info, with gratitude to those who care enough to provide it.
Then the room. When you pick a good mic, its going to do its job well, which may include picking up sound artifacts from the room. I have found that treating my corners, and ceiling have tamed a bit of the 'room monsters'.
Then the preamp \ converter \ cable team. You can go a long way with value based electronics, no doubt. The world we live in has demanded more for less and we win every day. However, that pre amp can really improve the sound quickly. Take some time and peek down that rabbit hole. Another chalk paint thing.
L