Desktop.
Monster desktop. In thirty years of scratch-building ever-smaller PCs and servers (most of them rackmounts), I've also taken a tip from the gaming community and returned to the world of honkin' big towers.
Re AMD vs. Intel, my experience mirrors your own. My last audio workstation was a scratch-built AMD and unreliable as hell. Random BSODs and system lockups were so predictable, in fact, -
once every two or three days - I had Sonar doing automatic saves every five minutes.
My latest machine is a scratch-built Intel i7 with dual SSDs in a RAID 1 configuration.
[Can you tell I have zero tolerance for failure anymore?] The hardest part of this build was finding a motherboard that supports legacy PCI for my Lynx AES16 digital audio card. Thankfully, there's still a few motherboard manufacturers making new products with PCI slots, and I've been very pleased with this Asus P9X79 LE. I hate to jinx it, but even on Windows 10, this is proving to be my most reliable audio workstation yet.
If you're interested, I composed a blog article and time-lapse video of the build, complete with parts list:
Scratch Building the Audio Workstation of Penultimate Doom. These things get dated pretty quickly, but maybe it can help?
Good luck!