Another knobby technique I've used with FX chains is to apply a gradient from the initial knob rotation to the end. For example a knob can get brighter as something gets "louder," or you could have a panpot go from red (left, for port) to green (right, for starboard) as you rotate it.
For an example of how this can be done subtly, check out
FX Chains > Anderton Collection > Processors > Graphic EQ. The knobs get more red as you boost, and more blue as you cut. For an over-the-top example that possibly indicates mental issues

, load
FX Chains > Anderton Collection > Drums > Psychedelic Drums.