"Glitches every few seconds" is actually good news (in terms of troubleshooting).  Something is in a polling state that wasn't before.
 
Run this to try and identify the culprit:
 
http://www.resplendence.com/latencymon

So it doesn't appear to be a generic problem. Time to have a dig around under the workstation hood I think :-)

This update will enable many things that were previously disabled. All my video and onboard sound devices were turned on again, so a conflict could be possible. No issues here because I knew this would happen and reset everything before I did any audio work. You have to go through all the system settings and check them along with a look at the device manager to see if audio or wi-fi hardware was reset.

Check for an audio device coming from your gfx cards

I have no issues here at all. If anything it seems to be smoother. That is highly speculative on my part. It works well that is for sure. I did upgrade Wordperfect from X5 to X8. LOL
 
I have the anniversary upgrade on two machines at present. Both work well. 

NNNNoooooooppppeeee   Not gonna do it!!

Thank you guys! I will try re-installing this update again and try to find the source of problem in two days since I have to record drums tomorrow and have everything running perfectly so I have to stay with the stable previous version of Win10 until then.

I reinstalled the update today and just after that I noticed that the Windows turned on NVIDIA audio drivers again. I needed to turn them off. You can take a look where is it if you have a problem like I did (it's Device Manager).

After turning those Nvidia audio drivers off everything's fine fortunately and audio glitches are gone.

Whoops, I was happy too early.. Those glitches just came back. :/
Take a look at this guys, maybe someone can help?
 

EDIT It looks like those glitches are gone for some time and they like to come back for a couple of minutes and then everything's ok etc. 
EDIT 2 Second time I launched LatencyMon it showed me 2240 hard pagefaults from wudfhost.exe  just in 31 seconds. It seems to be the one that is causing audio glitches. Anyone knows how to fix it? 

just to jump on the 'Don't update yet' bandwagon...  I updated and XLN updater is crawling, and all my Waves stuff is not working after refreshing it.