PS: If you are going to do a bunch of layering to smash a bunch of effects this is an EXCELLENT use for the new Aux Tracks. Basically set up a bunch of Aux Tracks and feed the original vocal track into all of them. Then add your effects on the different Aux tracks.
That way you aren't loading up the project with extra clips by cloning the original (which can slow down the system/be hard to keep track of) or busses (better to keep all your vocal mayhem in a nice neat folder in the Track Pane).
It also gives you a bunch of extra options as far as automation AND you can use the PC QuadCurve EQ on every Aux Track (you can only have one QC instance per track).
aaaaaand they can be recorded into (unlike busses) which means you can do realtime effects, record them into the Aux tracks then mangle the resulting clips further/individually with DSP and/or Region FX or whatever.
Then it can all terminate into a single bus (or multiples if you want) for final sound sculpting.
Also you can mute the main output of the original dry track (while the sends to the aux tracks are still active) to completely take it out of the equation OR automate the output for a wet/dry effect (but you have to make sure the sends to the Aux Tracks are PreFader).
Just some extra ideas for extra mangly goodness.
Cheers.