patm300e:
No, I don't always ensure the timeline is in sync with the tempo. In fact, when I'm recording audio practice tracks for performers, the templates I use simply set the timeline in the project to 60bpm so that each beat in the timeline is on each second of the recordings. (Note, this requires me to manually set some tempo based effects rather than rely on the tempo sensing capabilities of the effect.)
In the rare event that I need to add MIDI percussion clips to reinforce or supplement the audio tracks, then I'm required to align the timeline with the tempo of the recorded audio.
Hope this makes sense,
Paul