Softube are having a big problem with their plugins on 64-bit Win10. It's an admitted bug, and one that the support tech claimed was the biggest he's seen since working at Softube. All of their VST x64 plugs crash Studio One v3 when being scanned. SONAR Platinum seems to handle them OK, but that doesn't mean that the bug isn't affecting you in a less obvious way.
In any case, SPlat Lifetime is, IMO, the best audio software deal going today. I have no regrets for switching to SONAR from S1. The lifetime offer was a no-brainer for me (Which brain did you take? Um, Abby. Abby Normal!).