Since the latest update to Version 22.5 Build 45 2016.05 (x64) the playback in the Melodyne Region FX window is now about half a bar out of sync with the sound (the now time line is ahead of the sound). I've never seen this before and it started with this latest update. Clicking the Melodyne blob sounds the right phrase, it's just the playback that is now out of sync. Create a Region FX and just playback, listen and watch. Melodyne Studio, separate from Sonar Platinum if that makes a difference.