Kalle Rantaaho
Like Mettelus, I'm most puzzled by the interference follows the speaker-part. That alone cripples most of the suggestions above. That combined with the fact that the interference occurs only when a SONAR project is open makes it really weird.
Actually, it's so weird that I'm tempted to believe there's some accidental inaccuracy in the problem description, as the issue seems almost impossible to me. How could the loudspeaker know if it's connected left or right...what kind of a malfunction in monitors/cables could cause noise only when a certain software is open.
Truly bizarre isn't it. Yes, let's call the problem-speaker speaker B. When I have B on the left, the noise is on the left. When I have speaker B on the right, the noise is on the right.
The speaker alone can't be blamed as it only makes the noise when the 'audio engine' in SONAR is running.
SONAR/Focusrite unit alone can't be blamed as the noise can't be heard in headphones!
Whatever the issue, tough, it does seem that one speaker is more resistant to it that the other. Cheers!