Less than 8gb of ram in Windows can be an issue where memory can bottleneck the speed of the computer but once you cross that threshold, almost anything you throw at a Windows machine that slows it down is in no way related to memory. Your bottleneck is in some other part of the config. 128gb of ram is overkill in the biggest sense.
As an earlier poster suggested, cut back to minimums and give it a try, OS drive, Data Drive, Sample drive.
I have a feeling the backup drives are the problem.
I would avoid using any real-time backup programs or routines.
Having an extra drive to save duplicate projects to (I suggest BUN files if doing this) can be ok, but real time backup, especially raid setups, can slow you to a crawl. Some folks sort out real time backup but if something conflicts or is set oddly, it can kill you.
Also, Win 10 has all the virus protection you need built in so make sure you don't have any system choking 3rd party AV or malware stuff running.