Maybe try to find the .exe in M-Audio folder (Program Files\M-Audio I would guess), right click and choose compatibility mode there as well. It might be worth a try.
All the best.

Unsurprisingly, since these are drivers, there are no .exe files, only .sys & .inf entries. And probably .dlls in the windows system folders. None of these seem to be subject to running in any kind of compatibility mode.
 
I've had contact with Cakewalk support and been told that it's likely an issue with the drivers, and suggested using a mode other than ASIO. I gave it a shot and there was no improvement.
 
I'll defer to their expertise and accept that it well could be drivers, but I do have one nagging doubt: Why does X1 work perfectly with the same hardware and drivers that X3 chokes on?
 
Guess I'm left with the following choices:
 
1) Stick with the older X1, sacrificing advanced features of X3 that I don't use anyway.
2) Continue to limp along with X3, which seems to work ok once I get the control panel awakened, back up frequently  and hope I don't hit the 'Freeze!' button. (If I knew which one it was...)
3) Look for an inexpensive replacement multi-channel interface that will let me record 8 channels simultaneously, as the Delta 1010LT did. Yeah, I know... right after I find the unicorn farm...
 
Thanks again, Ken. I really appreciate your interest in helping.
 
Sigh,
Chuck

I meant the software panel, not the driver(again sorry). It has been a few years since I had my 1010, and it was under Vista/7. IIRC I had it running under X64 Win7. I always used ASIO with it.
Agree with it being strange that it works in X1, and not X3. This leads me to believe that there is hope.
You might need the help of someone with more skills than me, though
All the best.