yellowcake64
It's a good call Beep. I guess this could happen intermittently?
Dave
Well if the system (or more accurately Windows) decides to make some kind of beep or blop or boop the it could (depending on the settings you have) reach out to the interface to do it. Windows sounds are 44.1 16bit by default (I think) so if your project is something different then it takes over the interface and changes your settings.
Or something like that. Best to just have Windows Sounds disabled anyway even if that's not the problem.
The other issue it could be... now that I think of it... is a faulty connection. So if that's a USB device then maybe your cable is pooched or your USB port is pooched. That would explain why you lose all sign of the interface in your Prefs (if that's what's going on).
So in that case try a new USB cable or switch to another available USB port on your system.
If you switch to another port though it's probably a good idea to disconnect the device, uninstall the driver, reconnect the device to the new port and then reinstall the driver according to the manufacturer instructions.
Also make sure you have the most current driver for you device and operating system (of course). I would also say that sometimes the LATEST driver may not be the best thing so maybe do a google search of the device and drivers to see what other users are experiencing and be very careful if the driver install includes irreversible firmware updates (like my Focusrite does).
Usually you'll be fine but it's always best to go in armed with as much info as possible.
PS: I am not a computer tech. Just an ultra meticulous and paranoid bugger when it comes to this crap and have had USB connectivity issues in the past.
Hope it works out.
Cheers!