Yes, the signal is still there if I remove all the plugins (although I can only tell that from the peak meter - it's too quiet to be audible)
However, the culprit DOES appear to be the ProChannel. I never use the ProChannel, and haven't (intentionally) done so this time, either. But when I opened up the strip, and clicked Global On/Off at the top, the noise stopped.
I then turned it back on, switched each of the modules off on, and found that the culprit was the compressor at the top. Turning that from 100% wet to 100% dry stopped the tone.
I can't reproduce this on any other tracks; but I can switch the tone on or off via the ProChannel for both my affected tracks. Very strange, and not very welcome!
Unless there is some sort of vintage compressor that randomly emits a 490Hz hum, I'd say this was a bug. Is anybody else seeing behaviour like this?