I've had an XR18 digital mixer running with Sonar for several months now as an 18x18 USB interface on ASIO driver. For the most part I absolutely love it. There are some instances where I see a little difference in behavior from Sonar while it's been in the place of my RME, but those seem to be on projects with a mix of 64 and 32 bit plugs, so it's hard to attribute 100% to the interface.
I did go from PCIe to USB 2, which really may not even be a real factor for my lightweight use, but it did give me pause. The GUI interface, which just got an update today BTW, is gorgeous and intuitive, as it's just like a live mixer. I've got four independent stereo effects busses and compression on each channel as desired for monitoring. I can run headphones and three stereo monitors off it, and it interfaces MIDI to my Kurzweil. It also does some kind of ethernet P16 monitoring, which I've not even looked at yet, but I understand adds lots of monitoring flexibility with some add on devices. Then I can gig with it, which really is it's primary function, and for that it's just incredible.
At home and gigging I have it hardwired to an ethernet switch with simultaneous control from whatever it sees on the network including IPAD control VIA WIFI provided by the LAN. I've not used the internal WAP on it as I prefer keeping a wire on it. I see the IPAD control as icing on the cake and not required since you can control from the computer. But it has worked great and I'm happy I got it. Almost sent it back because I initially thought it was controlled *only* from the IPAD. Then realized I could run it over ethernet from the computer, then I saw the interface and realized the power it had, so I kept it. The preamps sound meaty, it's responsive, the processing sounds great, today's update looks fantastic, hence I've decided shared my experience. They've not put out an updated ASIO driver since the first one, so I hope that's approaching soon.