When I work without audio , I regularly crashes ...

The program crashes and I have to redémarer the computer ...

When I redémare I : (pending ) HuDNow this program prevents you from redémarer windows .

It's very embettant especially when you have not made a backup.

Please post your computer specs and equipment (see my sig) and there are many folks who can help diagnose your problem and get it sorted.

Marc
Sonar Platinium
version 21.11.00 Build Lexington - X 64
Tascam US - 16 X 08
Windows 7 Pro Service Pack 1
Intel Core i5 - 469OKCPU@3,50GHZ]469OKCPU @ 3,50GHZ
Ram 16 GO
SSD 250 Go / Disk dur 1000 Go
Systeme 64 bits

Your specs seem fine, although I'm not sure if SP1 is the latest on Win7.  Are you using the ASIO drivers for your Tascam?  What are your driver settings (e.g. buffers, latency, etc.)  You should update your Tascam drivers to the latest (if you haven't already.)
 
Are you running any other programs along with Sonar (like a web browser, MS Office, etc.)?
 
Let us know, we'll get to the bottom of it. 

Any 32bit plug-ins being used?
There is not much to go on in the OP.

I started with a Lexicon Alpha , the problem was the same.
This is when I work on the score with the mouse, I feel that sometimes I go too fast and the program crashes ...

Can you describe the exact steps to cause the crash?  Also, what are your ASIO settings on your Tascam?

The drivers are days , everything is ok at the sound card and sound card on another I have the same problem.

It crashes when I go too fast with the mouse ...

Is it possible that this is due to the mouse?