I have used Brainspawn's Forte since 2006, for live performance, and I am currently running it with literally 20+ instances of Kontakt and several instances of Arturia synths and Reaktor, and even a smattering of Korg Legacy Collection synths, with ZERO issues.
Forte has been bulletproof for me for the past 10 years, and does a magnificent job of allowing presets (snapshots to them) from any combination of any of the loaded synths and effects, further supporting splitting controllers into multiple zones, filtering and remapping of midi data, transposition, etc.
Furthermore, I can tell it - on a preset by preset or a global basis - to have individual synths not reload samples on a preset change - HUGELY powerful - as this gives me the ability to INSTANTLY switch between presets without having any sample load time at all.
They have a fully functional 30-day trial (might have a 30-minute session limit or something reasonable), at
www.brainspawn.com They have also been quite speedy and helpful on the 2 occasions I have requested tech support in the past 10 years. It has never failed me ever, and has been a complete joy to work with.
They even have a 'stress rack' test mode that will automatically switch between all of your presets over and over again for as long as you want to run it, so that you can make sure everything is cool prior to relying on it in a live situation. I believe Marillion has used it for about as long as I have.
I believe there is an additional $49 bit of software you can pick up from them that may allow you to send out midi data to externally do things like control lighting sequences and such (though I do not have that - as I am typing this that capability might be in the more robust version of Forte, rather than an additional piece of software, but you can see on the site which piece allows that sort of thing).
I am able to create incredibly lush layering of sound, and switch to altogether different sets of sounds instantly - you can even have control over it holding the last sound from one preset after switching to a new preset, until I lift up my fingers, and then it will switch in between with the next key strike being on the new preset - OR you can have it not do that. Total control of that sort of thing.
You can also set up a whole series of presets and then arrange them into whatever is needed for a given Song.
Lastly, I use a midi pedal board controller (Behringer FCB1010) because it has 2 midi expression pedals, and I can change Forte presets using either the foot switches or I can punch in preset numbers on my Axiom Pro 61 midi controller, depending on whatever my hands or feet are doing - and the midi expression pedals can be assigned to volume or wah, or both for volume for different instruments or whatever.
I LOVE using Forte - one of the most bang for the buck rock solid pieces of software I have ever purchased.
Bob Bone