if you watched the live stream from props the other day , there is a few "gotcha's"
e.g. the synths etc that use midti /audio stuff . I'm guessing things like sugar bytes artillery and a few more things like that.
neutron is another interesting one as it's the the "guess" function.. which well depends on how reason is dealing with the audio and summing perhaps/
you use vst's in that, you can't use them in rewire.. which is a pity, in the sense of they should have a sort of export function to help with that perhaps.
it's a start, but not enough.
and things with none standard browsers without fxp / fxb are still a pain ;-)