Hi, Ampy...
To the original query... yes you can totally use Drum Replacer to snag transients from any wave file and then create a percussive file based on that (AND use any sound you want to be triggered by the transients detected in DR).
BUT since you are having some kind of issue with your region effects... and even though you don't want to troubleshoot... I'm gonna offer a couple suggestions anyway.
Obvious... make sure you select the CLIP (and only a single clip) you want to apply your region FX to. These need to process the waveform. You may want to slice up the clip into smaller bits to make the process easier on your system (the longer the clip is the more processing needs to happen so doing it in chunks can help keep your computer from going haywire... IF that is the problem).
DON'T select the track (because it will select ALL clips in the track and therefore the Region FX will try to process ALL those clips... AFAIK).
The other thing if that isn't the problem would be to uninstall and reinstall the Region FX programs causing you issues. Drum Replacer is a separate installer from the main Sonar package and IIRC there was actually an update to it so maybe you are on the older version.
Melodyne Essentials is also a separate install.
The only other region FX you would have (AFAIK) would be V-Vocal which would require a custom install from a previous Sonar bundle to get at that effect on its own.
The Drum Replacer download will be in your account and available as a separate download if you want (no need for the CCC). Not sure how you would uninstall it.
The Melodyne Essentials download needs to be obtained from the Melodyne site (and registered through them).
Of course Cake support could give more detailed info.
Cheers.
Edit: Sorry... I forgot about Vocalsync (another Region FX). I think that is a separate download as well and the "apply to single clips" and "smaller clips are better" concept still applies... except for that tool you need to select a guide track and the track to be adjusted.