USB 2 is fine, although USB 3 is now becoming commonplace. USB 3 is far faster than anyone needs right now, yet is still backwards compatible w/ 2 for the most part (check first). Firewire is still viable through pci cards, which means desktop. It is more efficient than USB, but again, it is fast enough for all practical purposes. If you need 32 channels at once you need to go to MADI or Dante.
What I'd get is Burl for ADDA, but that is tré expensive (about $6000 for a 4 X 8 configuration, their smallest and you still have to get that sweet sound into your computer so save another $1000 or 3). The best buy right now is the TASCAM uh7000 for my money. $400 for a 2 X 2 USB 2 interface. Top of the line conversion and preamps. Latency can be a problem, but it also uses spdif or AES digital, so you can plug it into many other interfaces that have those connections. Most of the lower-priced interfaces are about the same sound and spec wise - you just need to make sure it works on your system. Even RME, considered to write the best drivers for both latency and stability (neat trick that) can have problems with any particular PC system. Every driver can have a problem, so it is best to buy one you can return and get one that does work. Focusrite is a favorite here, with TASCAM (the new hardware company associated w/ Cakewalk since Gibson own both) making waves with their newer line of USB interfaces (the uh7000 was a bit earlier tho the preamps share the same topology, I believe). And they are cheap, starting at $150 for stereo and only twice that for the 16 X 8 unit.