If I were you I would join their forum and ask there. A lot depends on your setup. If you have a monster computer, you can pretty much do whatever you want. Me, I use several different libraries, EW, GPO, Vienna plus Dim Pro and Cinematic Strings. I use one or two synths of each, and have just a handful of inst's on them. I have heard that maxing out a synth with all 16 channels is not a good idea, the sound quality may suffer. But one inst per synth does drain resources. So perhaps split the difference, have something like 4-6 inst's on each instance. That way also you can group like with like (woodwinds on one, brass on another etc). This helps with applying FX like reverb also (less on strings, more on woods, more yet on brass etc). You will get lots of specialized help on their forum.