Yes, of course you'd have "4 sides", but I'm thinking that might not necessarily be a problem if they're close enough together. They'd be separated by 18", which is nearly 3x the speaker diameter. I know in hi-fi enclosures that would be a no-no. But I'm thinking that might only be an issue less than 2' away from the cabinets.
Bat, thanks for the link. I'd actually found that link during my google research. "Holy Crap" seems to be the common reaction when people first use this box. They all rave about how good simulated Leslies sound, as well as ping-pong tremolo EP patches. Organ, Rhodes, Wurly and Acoustic Piano make up 99% of what I do live, so if the thing is loud enough it sounds like just the ticket.
As for relying on room reverberation as Paul points out, I don't see that being a major concern. You can adjust the M/S balance to compensate for more- or less-reverberant rooms. The big problem would be outdoor venues, but in that case my keyboards would be going to the FoH and the Space Station would just be for monitoring. I've blown up speakers and amplifiers (talking actual smoke) on outdoor stages so I don't even try that anymore.
Prior to finding this device, I'd been planning on using a pair of Roland keyboard amplifiers set as far apart as possible. But that's heavier (got a bad back) and more expensive, and the audience really only experiences the stereo effect if they're directly in front of the stage. The Space Station is supposed to give a stereo sense even in an adjacent room.