OK, here's what I think you need to do. If you haven't already, download and install the X AIR Edit application for Windows. Run the app and click on the "Setup" icon at the top-right. Now click on the "Mixer" tab of the setup page, and look for "USB Interface". There is a radio button for 18/18 ch or 2/2 ch. My guess is that you need to select 18/18 for all I/Os to be available. I would guess that the 2/2 option is just for recording the main stereo bus of the XR18.
Try it out and let us know how you get on. I just downloaded the app to see if I could figure this out for you. I don't actually have the XR18 yet - saving my pennies. Good luck.
Bill.