Hi, Geoff... you going for a flight case type set up for your live gigs? Some nice stuff out there for that kind of thing and you can get them customized. If I were going that route (and have dreamed about such things) having an in case conditioned power strip and even onboard cooling fan or having the option of removing panels for extra air flow are things that, to me, would be worth the extra cost. I'd even see if my metal worker buddies could weld together/rivet something with some tap and dye work so I can install fans and a power supply set up.
That is luxury though and probably more expense/PITA than you want to deal with so defintiely... extra room = better and wheels... definitely. I'd also make sure you have good sturdy handles strategically positioned and check out shock absorbing features to keep the guts of your gear from getting jostled around too much.