Yes it doesn't make sense, yet the only thing that changed on my system was the install of BA v3.0.8 + CbB v4.28 + The install of optional extras (excluding Melodyne). After checking out the great update, I switched back to finish off a 32 bit project in Sonar VS. And on starting up everything was a mess ... VS couldn't find any instruments, ReWire's missing and option greyed out, DX + Sonitus plugins not found.
To try to solve the problem I reinstalled Sonar VS + FLS10 (ReWire client) but surprisingly it didn't help on the situation. I then un-installed CbB, no difference, BA ... no difference. I was thinking about rolling back the system to a restore point, but gave one last try ... and installed the last 32-bit version of Platinum ... and all problems where gone.
At the time before the problems starting I had the following Cakes installed, Sonar VS, Sonar Home ed (32-bit), Sonar Platinum (x64 bit), a demo of Project5 v2, and BA v3.0.6. I can't say for certain that there is a connection to BA v3.0.8 and CbB v4.28. Will finish of the current project before I re-install BA and CbB, will update result of it here soon. It's probably just a coincidence.