Well
I think I can for certain things but I also think my hairline is exactly where it was when I was 18 and that chicks really dig scrawny, twisted up weirdo cripples.
So yeah... could be totally in my head. lol
Seriously though I've dropped to 48 and if I've lost anything it's minimal and I mix around it anyway. As I am learning more I may bump it up again for stuff I intend to fully release (for use in movies or whatever) but just for demos or fun stuff 48 is more than fine and what was used (AFAIK) in the ADAT days which was what the industry used for quite some time. No real reason to take the performance hit unless you have a specific need.
Bumping up from 44.1 for new projects would likely be a good idea though.
Cheers.