Yes. It is a two-step thing, first whatever you are using for the piano sound must respond to pitchwheel events in a known way (two semi-tone total bend, for instance, for the entire pitchwheel bend of 16384 ticks, or perhaps two semi-tones up and two down) . Then for each note in your demonstation, add a pitch wheel command calculated to change the tuning by however many cents you need. As an example, for a Pythagorean major third, compared to an Equal Tempered major third, compared to a Just Intonation (Harmonic) major third: the first would bend the third up 8 cents, which would be about 306 ticks for the 2up/2down pitchwheel bend setting; the second, of course, no bend, and the third would bend the third down about 14 cents, or about 540 ticks for the same setting. The Pythagorean and harmonic tunings are generally a "comma" apart, a little more than 22 cents.