Any idea why I can't get any sound out of omnisphere 2 when I insert it as a simple instrument track (have checked all routing and midi etc).  The only way I can get it to work is to set up a midi source track and an associated First synth audio outpur stereo audio track which just clutters up my screens.  I much prefer using simple instrument tracks
 
Thanks

Works here.  Are you selecting a MIDI channel for the output side?  If you do, make sure it matches the channel used in Omnisphere. 

Doh....sometimes my stupidity surprises even me :-)
 
Thanks for your help

Ha, not stupidity... I only knew to check that after sitting at the computer a couple of times wondering why I couldn't get sound out of Omnisphere... forgot it once or twice even after the first time I figured it out. :)