CJaysMusic

Your sample libraries are affected and decide if needing resampling to render later on.

LFM, MIDI Data is not effected by sample rates. Its data, not sounds. MIDI is not audio and audio is not MIDI. Audio is effected by sample rates and MIDIO data is not
 
CJ

Sure it is, but sooner or later it's to become audio - and already playing and recording there is audio driven by that midi - isn't that what OP was thinking about in the title of topic, to run 44k or 48k. Running 44k he could running digital out from keyboard and possibly get better quality was his thoughts - that's the connection midi as such.
But maybe I missed a point somewhere.