Earth Wind and Fire used a cool trick:
Record a real trumpet for the realness,... then add lots of other synth trumpets in unison. Big horn section.
while yearning for that option:
I would use multiple transpositions:
Clone the original track a bunch of times.
Use Sonar/Radius Transpose to move 12 steps. (experiment with settings)
Clone, detune, add slow modulation
Clone track: Transpose 12 steps
Clone, detune, add slow modulation
Use melodyne and repeat above.
Use the tracks that sound pretty OK not-too-bad. The 2 octave tracks will contain interesting harmonic distortion.
Could also try some other semi-free transposers. Reaper has some to try: Elastique is worth testing.
Not doubt combining a bunch of the different programs' result will at least give you something to work with.
And then find a real soprano add a couple of tracks to fix the formants.