Here's another example from my own experience. For the last two or three days I've been pulling my hair out because Sonar suddenly required 2, 3 & sometimes 4 tries to get it started. I'm thinking WTF?!
Then I remember I had been trying to get my Peavey AT200 to work with the MIDI interface in the 16x08. I unplugged the AT200 and Sonar is back to normal, screaming right along.
I like the new Sonar (X3e & up) much, much better than other DAWs I've used/tried out, but Sonar has always been more sensitive to its hardware environment that any other DAW I've used.
That's the reason I always think hardware when Sonar problems pop up, or even when they first appear with a new version of Sonar. That might sound like a problem, but right now S-PlatD is a screaming, rock solid monster for me.
I've never had a DAW that performed this well. So much so that I'm feeling pretty spoiled at the moment :)