If you want to see the picture at full size you can right-click on the image, choose copy, then open Paint and paste into it.
Many hours on sessions with big sample libraries
may be a memory issue. The great thing about 64-bit systems is you can load a zillion libraries into RAM, and 64 GB sure seems like it would be plenty for just about anything, but multi-gigabyte samples add up if they're left in memory even if you're not using them. Kontakt has a purge function to help with this, not sure about other samplers. Note that even streaming from disk uses up quite a bit of memory because the sampler has to store all the note attacks in RAM.
Might be worth getting into a workflow for a week or two where after two hours you save, re-boot to clear out the RAM, then re-open the project and see if the problem still occurs.