Danny,
I did a very quick retest with the audio metronome enabled. I don't have time tonight (or tomorrow) to try with audio tracks; sorry.
The audio metronome was set to play wave files (not MIDI note ons), on each beat (downbeat uses a different sound).
Here are the basic results, organized a bit differently.
1st column identifies the note (1st, 2nd, 4rd played...)
2nd column is the delta between note onset for Axiom track v. note onset for EMU track
3rd column is the delta between note onset for UM550 track v. note onset for EMU track
Axiom UM550
1 0 0
2 0 0
3 0 2
4 2 2
5 2 0
6 0 0
7 2 0
8 1 1
9 2 2
10 4 4
11 0 2
12 0 0
13 4 4
14 0 0
15 2 2
16 2 2
17 0 0
18 0 1
This time round, results were a bit different. The two USB interfaces did not always respond the same - sometimes the Axiom had jitter; sometime the UM550; sometimes both (and sometimes neither, of course). Also - sometimes the jitter was only 1 tick (0.5 milliseconds) - which surprises me; see earlier comment about 1 millisecond USB quantizing effect.
Max jitter was still about 2 milliseconds (4 ticks), relative to the EMU. And again, this is not a scientific test, and I wouldn't claim the results are terribly valid, or repeatable.
BTW - that seems like a pretty large MIDI setup to me. You have five different USB MIDI Interfaces! Plus a Firewire interface.
And the USB interfaces are made by several different companies (so, different drivers may be involved).
Could you remind me again of what problems you're running into, with that setup?
One thing you might try, is to plug four of the USB interfaces into a Belkin 'Tetrahub'. The Tetrahub is a USB 2.0 port -- that provides four completely independent, full-bandwidth USB 1.1 ports. That might get you more bandwidth per MIDI interface (because, if you have two USB interfaces plugged into a single 'root hub controller', they will normally share a single USB 1.1 channel. There are two USB ports per 'root hub controller', so it seems likely you're sharing bandwidth.) Anyway, the Tetrahub was about $40 when I bought one originally-- more recently, I got a travel version at a Bed, Bath and Beyond store for only about $20 - I think that was a GE unit, but it was also called a 'Tetrahub' - maybe a trademark ?
Good luck,
Jim