I do just about everything in stereo. Why? It gives dimension to the tune. I get a better effect in tracking two mono sources of the same instrument and panning those than attempting to use a plugin for that. I suspect most mixes are now a stereo construct IOW done on the mix as opposed to recorded with a pair of stereo mics.
I have used Waves Vitamin for some of the effect since it has the capability to decide a frequency and pan only the parts of the master you want to pan. The mid/upper mids are usually the areas I pan most in. When mixing for multiple systems I try to also make a mix that will come across in mono. More often I rely on M/S effects as opposed to a psuedo stereo plugin.
Another thing to remember is a wide image on studio monitors isn't the same image on headphones. I have recently been mixing more to headphones since this is probably 99% of the audience. Mixes on headphones tend to sound less spacial depending on the panning laws set. In order to sound spacial some of the sound must be thrown back to the other side and timed just right.
I recently picked up Boz Pan Knob on a sale and was surprised and what such a simple plugin could do for my panning and stereo image.