You shouldn't have to up the buffer size, unless you're at 48 samples or something like that. Generally 128 should be fine unless it's a particularly heavy project. You shouldn't be getting clicks and dropouts just from one synth. What about your sample rate? I generally stick to 48kHz. Is Rounds a Reaktor based synth? If so you can change the sample rate that Reaktor works at in the Reaktor settings. Although I have to say, I often run Reaktor synths at 96kHz without problem.
Have you tried the other synths in Komplete? If they're all fine then at least you have it narrowed down to Rounds. It's worth asking on the NI forums as well although they are notoriously quiet.
Honestly, with the system you have and the RME Babyface, you shouldn't be having problems like that. I'm not sure how you check latency issues on a Windows 8 system because DPC Latency Checker, which is the standard, does not report correct values on Windows 8 (this freaked me out on my new Windows 8 box when I first tested it, before I knew that DPC wasn't compatible with 8). I can generally have browsers open and be downloading stuff (I backup to a cloud constantly) with no cracks and pops in my audio. The only thing I can think of is if you have WiFi enabled - that's a notorious crackle causer.