C:\Users\
yourname\AppData\Roaming\Cakewalk\
SONAR Platinum\AUD.INI
Rename AUD.INI to AUD.old or whatever you want.
If you're not running Platinum, open whatever version you are running (all Sonar's installed will be there).
Might not hurt to rename all the AUD files in the various Versions.
Try that, you can't hurt anything, you will lose any "friendly" input/output names (take a screen shot prior to the change).
You will also have to re-set some the of Audio settings in
Preferences>Audio check them all.
AppData is a "hidden" folder, you might have to tell Windows to let you see hidden folders.
Solved a bunch of issues I was having with dropouts, snap, crackle, pop; simple projects, 2048 sample buffer; WTF?
My "Cat" is a little long in the tooth, but she still "purrs" up a storm, and RME drivers are rock solid.
I was at the point of contemplating a complete re-install of Windows; would've worked, that would have
deleted the AUD.INI file.
Best of luck, and don't ask me why it works.
I compared the before\after ini files (its a text file).
Order of "go", so to speak, was different; but I couldn't find a "problem".
"Gremlins"? That or Rockus and Rollus, the Gods of rock music, where just havin' some fun at my expense.
Again!

Tom