I want to add to the mouse/trackball comments here to say I've recently added a second trackball (Kensington Expert trackball/mouse, whatever they call it). It's helping a fair bit. I especially like being able to hold the mouse button down with one hand, while adjusting a control with the other hand (think faders and knobs). That action (adjusting faders and other controls) plus intense editing are the two actions that hurt my hands the most. By separating the 'click and hold' from the 'move' actions, it's helped. And, as you already know, just having the option to use either hand is a bit of a relief. Since both trackballs are seen as one (I don't install the Kensington software), it isn't possible to switch the left/right buttons on either one without affecting the other, but this hasn't been an issue for me.
Also, this is the wrong thread (should be in your other one about control surfaces), but I want to give a shout-out to the Mackie MCU Pro. Other than a couple of minor display issues (random characters that show in the MCU scribble strips), mine works just fine with Sonar X3e (and all X series). I like to mix and automate with it, I like using the transport controls, save buttons, buttons for switching between tracks, buses and outputs, and more. I wouldn't say I use it in a 'deep' way (haven't tried to use it for plugs or sends yet) but for the basics of day to day mixing, I'm very happy with it. There are others with complaints on the forum about lack of integration or bugs, but that has not been my experience at all. I use the USB port with mine, Win 7 64bit.