doesnt matter what motion I use, Ive tried them all, no matter what the behavior of some knobs are completely unpredictable. Like I wrote, only some knobs. But at least tell me that your prochannel is scrolling on turning knobs simultaneously? I doubt I can be the only one with that bug?

when turning knobs with mouse wheel I mean
 

My knobs don't move with the mouse wheel either.  Of course, why would I want to move knobs with the wheel?
 
Left-click, hold, and slide up or down for coarse settings. 
Hold the Shift key when you do this to get fine settings.

This works for me perfectly all the time:
1]Left mouse click on a knob or slider
2]The selected item shows a shading around it.
3]Using the mouse scroll wheel moves the selection. The knob CW/CCW; The sliders Up/Down.
4]Use the keyboard's +/- keys for fine movement.
I launched a series of VST's to see if this action is similar. Some does, others only acted by clicking on the knob and click hold-drag the mouse act.
 
Maybe a problem with your mouse or the Project Template.....

SimplemanZ:  The OP was having problems moving knobs in Prochannel, I assume not elsewhere.  I cannot move Prochannel knobs with the wheel; however, I can move all the other knobs with the wheel outside of Prochannel.  Both my keyboard and mouse are hardwired, no wireless junk. 
 
To avoid frustration, I simply use what works everywhere (the mouse act).  Not being able to make my hands play the bassline that is inside my head correctly is frustration enough!!

I finally figured it out - the buggy behavior appears when I have larger screen settings - high resolution but big icons and text etc.. .because I'm on a laptop and never liked this small text that you get with HD screens! 
SO, if your stuff cant fit the windows because of resolution you might experience funky behavior of knobs and sliders! 
So now I'll just stay with the large icon setting even if I don't like it..
Yeah, I would prefer to just use left mouse button when moving knobs and sliders, like on most apps.