Yup check the driver software.
First thing, regardless of whether you have the latest version or not please uninstall and install latests driver:
http://uk.focusrite.com/downloads?product=Forte As it's a USB driver install the latest chipset drivers for your motherboard, if it's an intel motherboard goto intel autoupdate. I would also update to the latest BIOS from your motherboard manufacturer.
Sometimes deleting AUD.INI resolves things (check these forums/google for details)
Finally get latencymon out (although this won't help the "greyed out" issue):
http://www.resplendence.com/latencymon Plenty of examples on how to use it in these forums.
On your next post should you require it I suggest you list your full system specs.
Ta.