Possibly a corrupt picture file
To recompute, right-click on the clip, click "Associated Audio Files..." at the bottom of the context menu then click "Recompute Picture(s)" on the Associated Audio Files dialog.
If the picture cache has never been cleared, it might be a good time to it. The location of the Picture Folder may be found in
Preferences > File > Audio Data. In Windows, go to the folder and delete all of its content.
To render Region FX, I use the "Render Region FX" option on the Region FX menu under the FX in use.