Well. I just tried the following sequence again and can reproduce the problem.
1. Plugin instance in audio track. Load a preset. Default wet/dry = 50%.
2. Wet/dry set to 10%. Close plugin. Reopen to verify wet/dry is still at 10%.
3. Project Saved
4. Project reopened and plugin opened. Verify wet/dry is as saved at 10%.
5. Hit PLAY. Wet/dry slider jumps to 50%
I'm at X3e x64 build 244 on Window 8.1 64bit.
Plugin is Eventide UltraReverb as a VST2.