Yea, I'm trying to gather more info, but to be honest haha...if I had more info I could probably fix the issue or at least see what it is myself. It's really that simple. When I add the plug-in there is no change and no effect. Turning it on/off yields no difference in the meters or via my monitors. I can tell it is not having any effect. Even turning the gain all the way up on the plug-in yields nothing different. It's simply not working. I can click the "On" button in the upper right hand corner and my track will completely mute, but that's the only effect it has.
I'm running that same version of X3 as you are Scook. And that IS the same plug-in I download form the link you provided.
Again, I can add this same VST to other Mono track/channels and it will work, it's just not working on my two guitar tracks. Quite annoying and frustrating. I have no idea how to begin fixing this issue.