If your computer is up to it, ie: you're not trying to run 100 tracks EWQL or whatever, there is no direct need to bounce soft synths to audio before mixdown.
An instrument track is simply a Midi track + Audio track merged together to make things easy. You supply it with midi, you get back audio. You can put whatever audio effects (including ProChannel) that you want on it.
If you find you're running low on CPU and your convolution reverbs are stuttering you can apply "freeze" to the instrument tracks. This does a temporary, reversible, bounce to track for that synth and then switches the synth off. You can still process the audio just as if it were a live synth, but you can't make edits to the synth or audio. To do that, you un-freeze it.