Sounds like the OP is behind on running at least Windows Update, if he has not connected to the web in one or more years. Drivers may also be behind the times, and even possible firmware.
To the original poster: It is quite possible that something is far enough behind in maintenance that you have started to have issues from X3e expecting a more current system. This has been the case with some C++ routines from Microsoft being out of date, for some other folks in the forum in prior threads.
I recommend you consider getting your Windows up to current maintenance levels for whatever version you are running (7 or 8 or 8.1), and also checking to see if there are driver updates for things like video drivers or even your audio interface.
I was having some weird but bad problems a couple of months back, and it turned out I was behind with applying maintenance to my audio interface drivers.
Bob Bone