I am not clear on the driver level you currently have for your M-Audio ProFire 2626. I saw where you indicated it had not been updated since you installed it, but the product web site drivers page indicates a version 6.1.1 is available.
You should be able to see what version of the interface driver software is running, and if it is not yet 6.1.1, then I would suggest you install 6.1.1, per their installation instructions.
The link for the drivers page for M-Audio is:
http://www.m-audio.com/index.php?do=support&tab=driver Just click on the appropriate attributes and you will see the link for your particular model.
I downloaded the drivers and looked at the Read Me file, but there isn't any explanation of what they fixed, nor what issues may remain, but it does seem to be the latest version, so I would suggest installing it.
Bob Bone