Well I kind of shifted the focus to the TC . I only use maybe 5 vocal presets and like you, mainly just on chorus...sometimes keep on whole song ..but then maybe a double or the " Thicker you" setting, since a distinct harmony would get irritating. I have no clue about using MIDI. I did get the Switch 3 pedal, which makes looping a lot easier, AND switch # 3 can be used to kick in an extra guitar effect at times! Without that, the guitar settings are global.
So back to compression, I was kind of fishing to see if there was was some stand out for acoustic. Apparently not. Honestly, for live play I don't think anyone, including me will really stop and notice compression taking place!! But I do at times go overboard for a hobbiest musician, seeking the best sound ...